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Last updateWed, 10 Feb 2016 7pm

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Introduction to Pressure Relief Devices - Part 1

Introduction to Pressure Relief Devices - Part 1

When the pressure inside equipment such ...

Is Your Company Ready for The New Reality?

Is Your Company Ready for The New Reality?

Since August, 2015, when VMA’s 201...

Offshore Oil Extraction and Transportation

Offshore Oil Extraction and Transportation

Offshore oil facilities come to the fore...

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Industry Headlines

Energy Sector Bracing for More Bankruptcy Filings in 2016

-1 DAYS AGO  |  Chris Guy

“In 2015, the energy sector accounted for more than one-half of all public company bankruptcy filings, including eight of the 10 largest filings...

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Industry Headlines

PM International Suppliers Joins VMA

-1 DAYS AGO

This week VMA welcomes PM International Suppliers, LLC as our newest associate member (distributor/channel partner), our 2nd new member of 2016 so far.

PM International supplies pipe and fittings, tubing, valves, flanges, bars, sheet and forgings with numerous worldwide sources for a wide variety o...

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ASCO Announces Brand Transition

18 HOURS AGO

ASCO Numatics, a business unit of Emerson, will begin doing business as ASCO, effective immediately. The transition to the ASCO name will be made on a global basis. It will not affect customer purchasing processes or sales channels.

The company said the ASCO name will leverage the power of its ASCO...

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Energy Sector Bracing for More Bankruptcy Filings in 2016

-1 DAYS AGO

“In 2015, the energy sector accounted for more than one-half of all public company bankruptcy filings, including eight of the 10 largest filings. Current oil prices and bond values indicate that 2016 will be another active year,” according to McGuireWoods Consulting.

“To account f...

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OPEC Anticipates Rivals Producing Less Oil in 2016

-1 DAYS AGO

OPEC projects world oil demand growth in 2015 increased by 1.54 mb/d, unchanged from the previous report, to average 92.96 mb/d. In 2016, world oil demand is expected to grow by 1.25 mb/d, representing a marginal lower adjustment of 10 tb/d from the previous forecast, to average 94.21 mb/d. Non-OECD...

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U.S. Job Openings Climb to Second-Highest Level on Record

22 HOURS AGO

The number of job openings increased to 5.6 million in December, the second highest number ever recorded, the U.S. Bureau of Labor Statistics reported today. Hires and separations were little changed at 5.4 million and 5.1 million, respectively. Within separations, the quits rate was 2.1%, and the l...

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Machine Tool Orders Rose in December, Down in 2015

22 HOURS AGO

The U.S. Manufacturing Technology Orders report for December 2015 showed that order values grew 20.4% compared to the prior month, according to The Association for Manufacturing Technology (AMT). For all of 2015, the year’s total orders were down 17.4% compared to 2014.

While the month-to-mon...

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The Biopharm Industry

vmwnt12_biopharm_cvr

This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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