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Industry Headlines

MSS Revises Standards for Instrument Valves, Sealing of Rising Stem Valves

1 DAY AGO

The Manufacturers Standardization Society (MSS) is pleased to announce the publication of the following revised Standard Practices:

  • MSS SP-99-2016a, Instrument Valves (replaces 2016 edition)
  • MSS SP-105-2016a, Instrument Valves for Code Applications (replaces 2016 edition)
  • MSS SP-120-2017, Flexible Grap...

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Spirax Sarco Celebrates 4 Years Without a Lost-Time Accident

1 DAY AGO

Spirax Sarco recently reached a safety milestone – 2.4 million man-hours, or 4 years without a lost-time accident, which means 288 employees did not miss work due to an injury suffered on the job. This significant accomplishment was celebrated  on August 10th with a fun lunch.

When asked why...

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Construction Underway on Atlantic Sunrise Pipeline

11 HOURS AGO

Construction is officially underway in Pennsylvania on the greenfield portion of the Atlantic Sunrise pipeline project – an expansion of the existing Transco natural gas pipeline to connect Marcellus gas supplies with markets in the Mid-Atlantic and Southeastern U.S.

Construction broke ground in ...

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EIA Projects 28% Increase in World Energy Use by 2040

15 HOURS AGO

The U.S. Energy Information Administration (EIA) projects that world energy consumption will grow by 28% between 2015 and 2040. Most of this growth is expected to come from countries that are not in the Organization for Economic Cooperation and Development (OECD), and especially in countries where d...

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Harvey Caused Steep Drop in U.S. Industrial Output

2 DAYS AGO

Industrial production declined 0.9% in August following six consecutive monthly gains. Hurricane Harvey is estimated to have reduced the rate of change in total output by roughly 0.75%. The index for manufacturing decreased 0.3%; storm-related effects appear to have reduced the rate of change in facto...

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Empire State Manufacturing Shows Strong Growth in September

2 DAYS AGO

Business activity continued to grow strongly in New York State, according to firms responding to the September 2017 Empire State Manufacturing Survey . The headline general business conditions index held steady at 24.4. The new orders index rose four points to 24.9 and the shipments index climbed four...

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The Biopharm Industry

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This segment of the chemical processing industry must deal with levels of cleanability and sterility that will ensure the safety of those who use or make the products.

As the world’s populations grow and age, developing countries expectations rise and new research brings new health solutions to the world, the biopharmaceutical (biopharm) industry flourishes. Like all chemical processing, biopharm has its own set of standards, special processing needs and challenges in materials and design.


THE CHEMICAL INDUSTRY

At its most general level, one can define the chemical industry as the aggregate of entities engaged in processing raw materials using chemical reactions (often aided by pressure and/or forms of energy such as heat) to convert those materials into products. That general level has numerous subgroups, such as biopharmaceutical, organic/inorganic chemicals, industrial gases, petrochemicals, agrochemicals, polymers and paints. These subgroups are categorized further by the end-product goods and commodities such as dyes, acids, alcohols, fertilizers, hydrogen, nitrogen, herbicides, ammonia, soaps, detergents, hair sprays, enamels, varnishes and many more.

Commonly, the processes required to manufacture these products use constituents or conversion enablers that are toxic, or they result in products and byproducts that may be toxic themselves. The inputs and outputs to those processes can present additional challenges because of physical and chemical properties that can make media extremely corrosive or abrasive. Also, the media can be difficult to propagate and control throughout the process flow in situations where physical/chemical properties result in media that is semi-solid.

In each segment of the industry and in every subcategory of these segments, valves play a critical role. A variety of valves are appropriate for various applications and deployed for handling different types of media. Covering the entire industry is too great a task for one article. Therefore, the information that follows highlights where and how valves are used in chemical processing for the biopharm market.


THE MARKET

The biopharm industry can be divided into two segments: Pharmaceutical, which uses chemical processes to manufacture therapeutic and health-related products; and biotechnology (biotech), which uses living organisms and biological processes to create products used in many fields such as pharmacology, medicine, agriculture and many others. A primary example is therapeutic protein used for medical and therapeutic applications. Most biotech applications involve cell cultures of genetically modified organisms including yeasts, insect cells, bacteria cells or mammalian cells.

A full range of pumps, valves and instrumentation comparable to other processing systems can be used in the biopharm industry. However, stringent requirements regarding cleanability and materials of construction mean that some products that perform ordinary and useful flow control functions in other applications must either be used with great caution or not used at all. An example is check valves. Check valves are installed tentatively because even sanitary check valves allow formation of “dead areas,” despite the fact they are functioning according to specifications. Such areas potentially harbor contaminants or toxic agents.

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